Research Insight

Investigational Subcutaneous Formulation of Vedolizumab Achieves Clinical Remission at Week 52 in Patients with Moderately to Severely Active Crohns Disease

Takeda Pharmaceutical Company Limited announced results from the phase 3 VISIBLE 2 clinical trial evaluating the efficacy and safety of an investigational subcutaneous (SC) formulation of the gut-selective biologic vedolizumab (Entyvio®) for use during maintenance therapy in adult patients...

Imminence of New Gonorrhea Therapeutic Drugs is Evident as the Bacteria Grow Super Resistant to Antibiotics

According to a new study, the gonorrhea therapeutics market will reach US$ 970 Mn in 2019, and estimated to register a 4% Y-o-Y over 2018. The gonorrhea therapeutics industry will remain influenced by increased attention on new developments in...

Road to Cell Death More Clearly Identified for Parkinson’s Disease

A pathway toward cellular death named for Thanatos identified by researchers as a key driver of nerve cell degradation in Parkinson’s disease Dopamine neurons are the primary cell type targeted by Parthanatos in Parkinson’s disease. Credit: The Dawson Lab In experiments...

Specific CD8 T cell states may indicate response to immune checkpoint therapy for melanoma

A multi-institutional research team, led by investigators at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard, has identified specific states of cytotoxic CD8 T cells that are associated with patient response to checkpoint immunotherapy for...

UCLA researchers develop mechanism for characterizing function of rare tumor cells

Scientists have long known that circulating tumor cells, rare cancer cells that are released into the bloodstream, have the potential to provide vital information about a person’s specific cancer. But until now, they have been unable to reliably access...

Preliminary Data from Study Demonstrates 94% Accuracy in Detecting Aggressive Prostate Cancer

VolitionRx Limited announced preliminary data from a prospective, multi-centered Proof of Concept Study of 84 men into the utility of Volition's Nu.Qâ„¢ assays to diagnose men with high-grade prostate cancer. At 88% specificity, the Volition panel of five assays (including...

Precision Medicine Researchers Identify New Alzheimer’s Genes

Researchers from Boston University School of Medicine, in collaboration with scientists from the Alzheimer’s Disease Sequencing Project (ADSP), have discovered new genes that could contribute to the onset of Alzheimer’s disease. The new discovery may advance precision medicine treatments...

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