Exelixis said it received upfront and milestone payments of $40.0 million when the agreement was signed in January 2007. Selection of the compound and opt-in by Genentech triggers a payment of $3.0 million and another $7.0 million is due when a mid-stage program is initiated by Genentech.
According to the agreement, Exelixis will be responsible for the first-stage clinical trial till the maximum tolerated dose is determined after which, Genentech will be responsible for completing the early stage trial and subsequent clinical development.